Knowledge on the Pathogenesis and New Diagnosing Techniques Approach for Low SARS-CoV-2 Testing Rates: A Case Study of Nigeria
Abass Abdulateef Ohilebo 1 2 * , Samuel Olarewaju Ogunsola 3, Abdullahi Tunde Aborode 4, Ademola Emmanuel Aiyenuro 5
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1 Department of Biochemistry, Ambrose Alli University Ekpoma, Edo State, NIGERIA2 Centre for BioCode, NIGERIA3 Department of Biochemistry, Federal University of Technology, Akure, Ondo State, NIGERIA4 Shaping Women in STEM (SWIS) Africa Research Hub, NIGERIA5 Department of Microbiology, Federal University of Technology, Akure, Ondo State, NIGERIA* Corresponding Author


SARS-CoV-2 (novel coronavirus responsible for coronavirus disease 2019) is a beta (β-) sub-class of the coronavirus which has caused more harm to live than expected. SARS-CoV-2 which was declared as a pandemic by the World Health Organization (WHO) on 11 March 2020, has caused governments globally to declare and implement the “lock down” policy for its citizen, including Nigeria with a large population in Africa. The country National Centre for Disease Control (NCDC) made it known the testing methods adopted by them are not effective at curtaining the large population of her citizens. Our main goal in this review is to focus on the SARS-CoV-2 pathogenesis and new diagnostic techniques approaches that can be adopted in Nigeria. A total of 88,432 testing has been carried out by the NCDC, with 14,554 confirmed cases in 200 million populations. Although the SARS-CoV-2 test adopted by the NCDC has been on the molecular testing using real-time reverse transcriptase polymerase chain reaction (RT-PCR) and antibody tests using blood, which has many demerits. We therefore recommend the NCDC should approach new diagnostic techniques like use of saliva samples and loop-mediated isothermal amplification (LAMP). Conclusively, when these methods are considered, testing rates will greatly improve.


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Article Type: Review Article

EUR J ENV PUBLIC HLT, Volume 5, Issue 1, 2021, Article No: em0064

Publication date: 04 Nov 2020

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